Week 2 Fantasy Football Game-By-Game Notesheet

Who to start and who to sit in Week 2

Sep 11, 2025

∙ Paid

Week 2 brings prime bounce-back opportunities after a turbulent opening slate. Major injuries (Brock Purdy, George Kittle), shifting backfields, and underperformances by wide receivers all headline the matchups. Here’s your comprehensive fantasy start/sit and target guide heading into the weekend, game by game.

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