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JHEN Fantasy

Cardinals vs Saints – Week 1 Fantasy Football Preview

Arizona’s rising defense meets a Saints offense led by Year 2 QB Spencer Rattler, while Marvin Harrison looks to make the leap against a New Orleans unit

JHEN Fantasy
Sep 02, 2025
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Line: Cardinals -6 | Total: 42.5


The market has Arizona laying six, and the totals suggest a slower, defense-tilted opener. Context matters here: the Saints’ defense isn’t as deep as years past, while Arizona’s D is trending up. On offense, Rashid Shaheed returns from injury to flank Chris Olave, and the Cardinals will lean on Kyler Murray and a balanced Conner/Benson backfield as Harrison pushes for a second-year breakout.

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